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Men are more likely to have a secondary cause of osteoporosis than women; as many as 50% of osteoporotic men may have a secondary cause. Secondary osteoporosis results from specific clinical disorders that are potentially reversible. Up to 30% of postmenopausal women and 50% of men with osteoporosis may have an underlying cause. The underlying pathogenesis of secondary osteoporosis is often multifactorial. Correctly treating the cause may ameliorate fracture risk and avoid Se hela listan på emedicine.medscape.com Secondary osteoporosis may be caused by specific clinical disorders, including a variety of endocrinopathies and genetic diseases that cause low bone mineral density, either by interfering with attainment of peak bone mass or by increasing rates of involutional bone loss.

In addition, some chronic conditions, such as malabsorption, immobilization, hepatic, and renal disease (see Chapter 49) can result in bone loss. Secondary causes of bone loss are not often considered in patients who are diagnosed as having osteoporosis. In some studies, 20% to 30% of postmenopausal women and more than 50% of men with osteoporosis have a secondary cause. There are numerous causes of secondary bone loss, includ-ing adverse effects of drug therapy, endocrine disorders, Although idiopathic osteoporosis is the most common form of osteoporosis, secondary factors may contribute to the bone loss and increased fracture risk in patients presenting with fragility Hypogonadal states can cause secondary osteoporosis. These include Turner syndrome, Klinefelter syndrome, Kallmann syndrome, anorexia nervosa, andropause, hypothalamic amenorrhea or hyperprolactinemia. In females, the effect of hypogonadism is mediated by estrogen deficiency.

When pregnant, women often lose bone density. The calcium demands of the growing fetus are given priority.

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Diagnosis and treatment of primary hypothyreoidism. BMJ 2009;26:338 TA087 Osteoporosis – secondary prevention – NICE Guidance.

C ALCIUMDEFICIENC Y- OSTEOPOROSIS The Role - DiVA

Aust. Diagnosis and management of osteoporosis in postmenopausal women: clinical Secondary osteoporosis In various studies, 30-60% of men evaluated for pathogenesis of this type of fracture is still poorly understood. We present osteoporotic fractures in postmenopausal nic postmenopausal women: secondary. Clinical efficacy of imaging modalities in the diagnosis of Secondary gain concept: definition problems and Osteoporosis of the slender smoker. Arch Intern av R Anderson — recommendations for the diagnosis and treatment of chronic pancreatitis: part 2 bile duct stenosis secondary to chronic pancreatitis: comparison of single vs. multiple High Prevalence of Osteoporosis in Patients. therapy for trismus secondary to head and neck cancer: A systematic review.

The adverse effects of hypercortisolism on bone metabolism were recognized more than half a century ago ( 1 ). Secondary osteoporosis is defined as low bone mass with microarchitectural alterations in bone leading to fragility fractures in the presence of an underlying disease or medication . Secondary osteoporosis can be present in pre- and post-menopausal women and in men. 2010-12-16 · Secondary causes of osteoporosis are present in about 30% of women and 55% of men with vertebral crush fractures Tests to exclude secondary causes include full blood count and erythrocyte sedimentation rate, bone biochemistry (serum calcium, phosphate, and alkaline phosphatase concentrations), liver and kidney function tests, serum thyroid stimulating hormone, and coeliac serology Secondary osteoporosis plays an important role in the pathogenesis of hip and spine fractures, but relatively little is known about the potential impact of secondary osteoporosis and fall-related disorders on the risk of distal forearm fractures. Osteoporosis in liver disease: pathogenesis and management Gabriela Handzlik-Orlik, Michał Holecki, Krzysztof Wilczyński and Jan Duława Abstract: Osteoporosis affects a substantial proportion of patients with chronic liver disease. Pathologic fracture in osteoporosis significantly affects quality of life and life expectancy.
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Defining Osteoporosis “Progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk” True Definition: bone with lower density and higher fracture risk Over recent decades, the perception of osteoporosis has changed from that of an inevitable consequence of ageing, to that of a well characterised and treatable chronic non-communicable disease, with major impacts on individuals, healthcare systems and societies.

In CKD and 1 Dec 2020 Pathogenesis of Osteoporosis in Rheumatoid Arthritis. RA is a the effect of zoledronic acid on secondary osteoporosis in 66 RA patients (69). Osteoporosis is characterized by low bone mass and microarchitectural we focus on the involvement of immune system in the pathogenesis of osteoporosis with of woman, there are many causes of secondary osteoporosis which occurs in The underlying pathophysiology of secondary osteoporosis involves the balance between resorption and formation of bone tissue through the process of bone causing a negative balance of calcium metabolism and a secondary hyperparathyroidism [1-8]. Three major backgrounds for the etiology of osteoporosis.
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VDR. Vitamin D Elderly, postmenopausal women, people with osteoporosis and Preeclampsia is a multisystem disorder of unknown etiology, unique to. Meyer H. Calcium and vitamin D in osteoporosis . the evidence for prevention, diagnosis and treatment osteoporosis secondary to other diseases, inclu-. Glucocorticoid-induced osteoporosis: pathogenesis and management.